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Effects of aerobic exercises in the management of subjects with chronic depression

Valeti Ashok Kumar 1*, Singam Siva Shankar 2


BACKGROUND AND PURPOSE: low mood and state of aversion to activity is generally called as depression that can affect person’s thoughts, behavior, feelings and sense of wellbeing. There are many ways to reduce the depression like pharmacological agents like anti-depressants and complementary therapies such as physical activity, exercise, modification of life style and dietary habits. Aerobic exercises usually change the brain activity and induce relaxation which may relieve depression and anxiety. The purpose of this study is to compare the effects of aerobic exercises along with Anti depressive therapy and Anti depressive therapy only in subjects with chronic depression.Aim of the study is to know the effects of aerobic exercises on subjects with chronic depression.

OBJECTIVES: To compare the effects of aerobic exercises along with anti-depressant          therapy and anti-depressant therapy only in subjects with chronic depression.

METHODOLOGY: 60 subjects with chronic depression were selected and randomly divided into two groups. Experimental group received aerobic exercises along with anti-depressant therapy and controlled group received anti-depressant therapy only.

OUTCOME MEASURES: Pre and Post treatment values of depression were analyzed by using Hamilton depression rating scale.

RESULTS: The results of this study were showing an extremely significant improvement in the overall depression levels in combination therapy group when compared to anti-depression therapy alone when assessed with Hamilton depression rating scale (P <0.0001).

CONCLUSION: In this comparative study aerobics with anti-depressive therapy is more effectively improving depression when compared with anti-depressive therapy only.


Chronic depression; Aerobics; Hamilton Depression Rating Scale

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Markus MacGill, Depression: Causes, Symptoms and Treatments, National Institute for Health and Care Excellence, Clinical Knowledge Summaries. Information published online, London, UK accessed 10 August 2015.

RW, Birnbaum AS, Kubik MY, Dishman RK (2004) Naturally occurring changes in physical activity are inversely related to depressive symptoms during early adolescence. Psychosom Med


Geneva, et al: Depression. World Health Organization. Information published online, accessed 10 August 2015.

Arlington, Virginia,; National Alliance on Mental Illness, citing information from the American Psychiatric Association. 10 August 2015.

Lana J Williams, Felice N Jacka, Adrienne O’Nei, Evidence for an immune response in major depression: a review and hypothesis. Prog NeuropsychopharmacolBiol Psychiatry 1995, 19:11–38.

Maes M, Berk M, Goehler L, Song C, Anderson G, Galecki P, Leonard B:Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways. BMC Med 2012, 10:66.

ELIZABETH Altar, C. A. (1999). Diagnostic and Statistical Manual of Mental Disorders Neurotrophins and depression.Trends Pharmacol., Text Revision, 4th Edn. Washington, D.C.: American Psychiatric Association. Sci. 20, 59–62. APA.(2000).

. William Coryell. In: The Merck Manual, Depressive disorders, Published online by Merck & Co., accessed 7 August 2015.

John Markowitz and Myrna Weissman, Interpersonal psychotherapy: principles and applications. World Psychiatry, 2004, volume 3, number 3, pages 136-139.

Singh NA, Clements KM, Fiatarone MA. A randomized controlled trial of

progressive resistance training in depressed elders. J Gerontol A Biol Sci Med

Sci 1997; 52: M27-M35.

. Blumenthal JA, Babyak MA, Doraiswamy PM, et al. Exercise and pharmacotherapy in the treatment of major depressive disorder. Psychosom Med 2007; 69: 587-596.

J.Sarris, S.Moylan, D.A.Camfield, M.P.Pase, D.Mischoulon, M.Berk, F.N.Jacka, andI.Schweitzer, ComplementaryMedicine, Exercise,Meditation, Diet, and LifestyleModification for Anxiety Disorders. Evidence-Based Complementary and Alternative Medicine Volume 2012, Article ID 809653, 20 pages doi:10.1155/2012/809653.

R. C. Kessler, T. C. Wai, O. Demler, and E. E. Walters,“Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication,”Archives of General Psychiatry, vol. 62, no. 6, pp. 617–627,2005.

Robert Hirschfeld et al., Differential diagnosis of bipolar disorder and major depressive disorder. Journal of Affective Disorders, 2014, volume 169, number S1, pages S12–S16, doi: 10.1001/archpsyc.62.4.417.

Marie Carmen Valenza , Geraldine Valenza-Pen˜a , Irene Torres-Sa´nchez ,

Emilio Gonza´lez-Jime´nez NR PhD, Alicia Conde-Valero, and Gerald Valenza-Demet, Effectiveness of Controlled Breathing Techniques on Anxiety and Depression in Hospitalized Patients With COPD: A Randomized Clinical Trial, respiratory care february 2014 vol 59 no 2.

Russo-Neustadt AA, Alejandre H, Garcia C. Ivy AS, Chen MJ. Hippocampal brain-derived neurotrophic factor expression following treatment with reboxetine, citalopram, and physical exercise.Neuropsychopharmacology. 2004 Dec;29(12):2189-99

Helmich I, Latini A, Sigwalt A, Carta MG, Machado S, Velasques B, et al. Neurobiological Alterations Induced by Exercise and Their Impact on Depressive Disorders. ClinPractEpidemiolMent Health.2010, 6, 115-125 115

Elder GA, De Gasperi R, Gama Sosa MA. Research update: neurogenesis in adult brain and neuropsychiatric disorders. Mt Sinai J Med. 2006 Nov;73(7):931-40

Yau SY, Lau BW, Tong JB, Wong R, Ching YP, Qiu G, et al. Hippocampal neurogenesis and dendritic plasticity support running-improved spatial learning and depression-like behaviour in stressed rats. PLoS One. 2011;6(9):e24263

Marlatt MW, Lucassen PJ, van Praag H. Comparison of neurogenic effects of fluoxetine, duloxetine and running in mice. Brain Res. 2010 Jun 23;1341:93-9.

Dimeo F, Bauer M, Vahram I, Proest G, Halter U (2001) Benefits from aerobic exercise in patients with major depression: a pilot study. Br J Sports Med 35:114–117

Knubben K, Reischies FM, Adli M et al (2007) A randomised, controlled study on the effects of a short-term endurance training programme in patients with major depression. Br J Sports Med 41(1):29–33. doi:10.1136/bjsm.2006.030130

Dunn AL, Garcia ME, Marcus BH et al (1998) Six month physical activity and fitness changes in project active, randomized trial. Med Sci Sports Exerc 30:1076–1083

Kodis J, Smith KM, Arthur HM, Daniels C, Suskin N, McKelvie RS (2001) Changes in exercise capacity and lipids after clinic versus home-based aerobic training in coronary artery bypass graft surgery patients. J Cardiopulm Rehabil 21:31–36

King AC, Haskell WL, Taylor CB, Kraemer HC, DeBusk RF (1991) Group- vs. home-based exercise training in healthy older men and women: a community-based trial. JAMA 266:1535–1542

Dunn AL, Madhukar H, Trivedi MD et al (2005) Exercise treatment for depression Efficacy and dose response. Am J Prev Med 28(1):1–8

Blumenthal JA, Michael A, Babyak A et al (2007) Exercise and pharmacotherapy in the treatment of major depressive disorder. Psychosom Med 69:587–596

Greist JH, Klein MH, Eischens RR et al (1979) Running as treatment for depression. Compr Psychiatry 20:41–54

Fremont J, Craighead LW (1987) Aerobic exercise and cognitive therapy in the treatment of dysphoric moods. Cognit Ther Res 11:241–251

Bonnie Meekums, Vicky Karkou, E Andrea Nelson, Dance movement therapy for depression. :19 February 2015, 10.1002/14651858.CD009895.

Gary M Cooney, Kerry Dwan, Carolyn A Greig, Debbie A Lawlor, Jane Rimer, Fiona R Waugh, Marion McMurdo, Gillian E Mead. Exercise for depression. 12 September 2013, 10.1002/14651858.CD004366

Liza Varvogli1, Christina Darviri, Stress Management Techniques: evidence-based procedures that reduce stress and promote health, Aealth Science Journal, volume 5, issue 2 (2011)


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